Circadian rhythm of serum total homocysteine in men

被引：26

作者：

Bremner, WF

Holmes, EW

Kanabrocki, EL

Hermida, RC

Ayala, D

Garbincius, J

Third, JLHC

Ryan, MD

Johnson, M

Foley, S

Shirazi, P

Nemchausky, BA

Scheving, LE

机构：

[1] MacNeal Cardiol Grp, Berwyn, IL 60402 USA

[2] Loyola Univ, Stritch Sch Med, Dept Pathol, Maywood, IL 60153 USA

[3] Edward Hines Jr Hosp, Dept Vet Affairs, Hines, IL USA

[4] John L McClellan Mem Vet Adm Med Ctr, Little Rock, AR USA

[5] Univ DeVigo, Bioengn & Chronobiol Labs, Vigo, Spain

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2000年 / 86卷 / 10期

关键词：

D O I：

10.1016/S0002-9149(00)01181-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serum homocysteine levels were examined in a 24-hour study of 7 healthy and 5 diabetic men, revealing a statistically significant circadian rhythm (p = 0.030), normal concentrations of 11.83 1.2 vs 12.99 +/- 1.2 mu mol/L, with peak values occurring during the evening (10:37 P.M.) and lowest levels occurring during the morning. These findings imply that increased atherosclerotic risk in insulin-resistant diabetics during morning hours does not appear to be explained by differences in homocysteine levels in the normal population.

引用

收藏

页码：1153 / +

页数：6

相关论文

共 21 条

[1]

Aarsand AK, 1998, J INTERN MED, V244, P169

[2] Plasma homocysteine concentrations in healthy volunteers are not related to differences in insulin-mediated glucose disposal [J].

Abbasi, F ;

Facchini, F ;

Humphreys, MH ;

Reaven, GR .

ATHEROSCLEROSIS, 1999, 146 (01) :175-178

[3] ROLE OF TRIGLYCERIDES IN CORONARY-ARTERY DISEASE - LESSONS FROM THE PROSPECTIVE CARDIOVASCULAR MUNSTER STUDY [J].

ASSMANN, G ;

SCHULTE, H .

AMERICAN JOURNAL OF CARDIOLOGY, 1992, 70 (19) :H10-H13

[4] Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women [J].

Bostom, AG ;

Silbershatz, H ;

Rosenberg, IH ;

Selhub, J ;

D'Agostino, RB ;

Wolf, PA ;

Jacques, PF ;

Wilson, PWF .

ARCHIVES OF INTERNAL MEDICINE, 1999, 159 (10) :1077-1080

[5] Relation between circadian patterns in levels of circulating lipoprotein(a), fibrinogen, platelets, and related lipid variables in men [J].

Bremner, WF ;

Sothern, RB ;

Kanabrocki, EL ;

Ryan, M ;

McCormick, JB ;

Dawson, S ;

Connors, ES ;

Rothschild, R ;

Third, JLHC ;

Vahed, S ;

Nemchausky, BM ;

Shirazi, P ;

Olwin, JH .

AMERICAN HEART JOURNAL, 2000, 139 (01) :164-173

[6] Plasma homocysteine concentration related to diet, endothelial function and mononuclear cell gene expression among male hyperlipidaemic smokers [J].

Brude, IR ;

Finstad, HS ;

Seljeflot, I ;

Drevon, CA ;

Solvoll, K ;

Sandstad, B ;

Hjermann, I ;

Arnesen, H ;

Nenseter, MS .

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1999, 29 (02) :100-108

[7]

DOMAGAIA TB, 1998, J CARDIOVASC RISK, V5, P234

[8] Inferential statistical method for analysis of nonsinusoidal hybrid time series with unequidistant observations [J].

Fernandez, JR ;

Hermida, RC .

CHRONOBIOLOGY INTERNATIONAL, 1998, 15 (02) :191-204

[9] Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins - The atherosclerosis risk in communities (ARIC) study [J].

Folsom, AR ;

Nieto, FJ ;

McGovern, PG ;

Tsai, MY ;

Malinow, MR ;

Eckfeldt, JH ;

Hess, DL ;

Davis, CE .

CIRCULATION, 1998, 98 (03) :204-210

[10] Homocysteine and atherosclerosis [J].

Gerhard, GT ;

Duell, PB .

CURRENT OPINION IN LIPIDOLOGY, 1999, 10 (05) :417-428