Targeting Rho in cardiovascular disease

被引:153
作者
Laufs, U
Liao, JK
机构
[1] Brigham & Womens Hosp, Div Cardiovasc, Vasc Med Unit, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Univ Saarland, Med Clin 3, D-6650 Homburg, Germany
关键词
GTP-binding proteins; gene regulation; cytoskeleton; isoprenoids; cholesterol;
D O I
10.1161/01.RES.87.7.526
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:526 / 528
页数:3
相关论文
共 20 条
[1]   HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth muscle and endothelial cells [J].
Bourcier, T ;
Libby, P .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2000, 20 (02) :556-562
[2]   Small guanine nucleotide-binding proteins and myocardial hypertrophy [J].
Clerk, A ;
Sugden, PH .
CIRCULATION RESEARCH, 2000, 86 (10) :1019-1023
[3]   REGULATION OF THE MEVALONATE PATHWAY [J].
GOLDSTEIN, JL ;
BROWN, MS .
NATURE, 1990, 343 (6257) :425-430
[4]   Rho GTPases and the actin cytoskeleton [J].
Hall, A .
SCIENCE, 1998, 279 (5350) :509-514
[5]   Translational control of p27(Kip1) accumulation during the cell cycle [J].
Hengst, L ;
Reed, SI .
SCIENCE, 1996, 271 (5257) :1861-1864
[6]   Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells [J].
Hernández-Perera, O ;
Pérez-Sala, D ;
Soria, E ;
Lamas, S .
CIRCULATION RESEARCH, 2000, 87 (07) :616-622
[7]  
Katsumata N, 1997, CIRCULATION, V96, P4357
[8]   EFFECT OF PRAVASTATIN ON OUTCOMES AFTER CARDIAC TRANSPLANTATION [J].
KOBASHIGAWA, JA ;
KATZNELSON, S ;
LAKS, H ;
JOHNSON, JA ;
YEATMAN, L ;
WANG, XM ;
CHIA, D ;
TERASAKI, PI ;
SABAD, A ;
COGERT, GA ;
TROSIAN, K ;
HAMILTON, MA ;
MORIGUCHI, JD ;
KAWATA, N ;
HAGE, A ;
DRINKWATER, DC ;
STEVENSON, LW .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (10) :621-627
[9]   Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by rho GTPase [J].
Laufs, U ;
Liao, JK .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (37) :24266-24271
[10]   Neuroprotection mediated by changes in the endothelial actin cytoskeleton [J].
Laufs, U ;
Endres, M ;
Stagliano, N ;
Amin-Hanjani, S ;
Chui, DS ;
Yang, SX ;
Simoncini, T ;
Yamada, M ;
Rabkin, E ;
Allen, PG ;
Huang, PL ;
Böhm, M ;
Schoen, FJ ;
Moskowitz, MA ;
Liao, JK .
JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (01) :15-24