Reaction of tanshinones with biogenic amine metabolites in vitro

被引：33

作者：

An, LK

Bu, XZ

Wu, HQ

Guo, XD

Ma, L

Gu, LQ ^{[1
]}

机构：

[1] Zhongshan Sun Yat Sen Univ, Sch Chem & Chem Engn, Dept Chem, Guangzhou 510275, Peoples R China

[2] Zhongshan Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510275, Peoples R China

来源：

TETRAHEDRON | 2002年 / 58卷 / 52期

关键词：

tanshinone; hepatic encephalopathy; biogenic amine metabolite;

D O I：

10.1016/S0040-4020(02)01414-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of cryptotanshinone and tanshinone HA with several biogenic amine metabolites involved in the pathogenic pathways of hepatic encephalopathy are investigated and eleven 1,2,3,4,-tetrahydrophenanthrene derivatives, 2-10, 14 and 16, are obtained. The probable mechanisms on reaction are discussed. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：10315 / 10321

页数：7

共 17 条

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