Triterpenoid saponins from leaves of Hedera pastuchowii

被引：21

作者：

Mshvildadze, V

Elias, R

Faure, R

Rondeau, D

Debrauwer, L

Dekanosidze, G

Kemertelidze, E

Balansard, G

机构：

[1] Univ Mediterranee, Fac Pharm, Lab Pharmacognosie, F-13385 Marseille 5, France

[2] Georgian Acad Sci, Inst Pharmacochem, GE-380059 Tbilisi, Georgia

[3] Univ Aix Marseille 3, UMR 6009, F-13397 Marseille 20, France

[4] Univ Angers, Serv Commun Anal Spectroscop, F-49045 Angers, France

[5] INRA, Ctr Rech Toulouse, F-31931 Toulouse, France

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2004年 / 52卷 / 12期

关键词：

Hedera pastuchowii; Araliaceae; triterpenoid saponin; NMR; MS; pastuchoside;

D O I：

10.1248/cpb.52.1411

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Five new triterpenoid saponins, pastuchoside A (1), B (3), C (5), D (7) and E (9), were isolated from the leaves of Hedera pastuchowii. They have oleanolic acid or hederagenin as aglycone. The structures were established by NMR spectroscopy including gs (gradient selected)-COSY, gs-HSQC, gs-HSQC-TOCSY and gs-HMBC experiments, and mass spectrometry (ESI-HR-MS). Heptaoside saponins, compounds 1 and 3, are described for the first time in the genus Hedera.

引用

页码：1411 / 1415

页数：5

共 16 条

[1]

In vitro activity of hederacolchisid A1 compared with other saponins from Hedera colchica against proliferation of human carcinoma and melanoma cells [J].