Biosynthesis of iso-fatty acids in myxobacteria:: Iso-even fatty acids are derived by α-oxidation from iso-odd fatty acids

被引：30

作者：

Bode, HB

Dickschat, JS

Kroppenstedt, RM

Schulz, S

Müller, R

机构：

[1] Univ Saarland, Inst Pharmazeut Biotechnol, D-66041 Saarbrucken, Germany

[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Chim Organ, D-38106 Braunschweig, Germany

[3] DSMZ, D-38124 Braunschweig, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 02期

关键词：

D O I：

10.1021/ja043570y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The biosynthesis of iso-fatty acids was investigated in the myxobacteria Myxococcus xanthus and Stigmatella aurantiaca by feeding labeled precursors of these fatty acids and by conducting detailed analysis of the fatty acid profiles and fatty acid MS and NMR spectra. These experiments revealed that in S. aurantiaca all iso-even fatty acids are formed via α-oxidation of iso-odd fatty acids and not by using valine-derived isobutyryl-CoA. Copyright © 2005 American Chemical Society.

引用

页码：532 / 533

页数：2

共 14 条

[1]

Borge GIA, 1999, LIPIDS, V34, P661, DOI 10.1007/s11745-999-0411-7

[2] ISOVALERIC ACID AS A PRECURSOR OF ODD NUMBERED ISO FATTY-ACIDS IN TETRAHYMENA [J].