Developments in glucocorticoid therapy

被引：28

作者：

Bijlsma, JWJ

Saag, KG

Buttgereit, F

da Silva, JAP

机构：

[1] Univ Utrecht, Med Ctr, Dept Rheumatol & Clin Immunol, NL-3508 GA Utrecht, Netherlands

[2] Univ Alabama Birmingham, Div Clin Immunol & Rheumatol, Ctr Educ & Res Therapeut Musculoskeletal Disorder, Birmingham, AL 35294 USA

[3] Humbold Hosp, Charite, Dept Rheumatol & Clin Immunol, D-10098 Berlin, Germany

[4] Hosp Univ Coimbra, P-3000075 Coimbra, Portugal

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2005年 / 31卷 / 01期

关键词：

D O I：

10.1016/j.rdc.2004.10.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recent evidence for a disease-modifying potential of low-dose glucocorticoids (GCs) in the treatment of rheumatoid arthritis has renewed the debate on the risk benefit ratio with this therapy. Two recent developments are described that might have a positive influence on these risk benefit ratios. One is the improvement in new GC compounds-designer GCs, alterations in bioactivity, and alterations in formulations. The other is a better understanding and management of the toxicity of GCs.

引用

页码：1 / +

页数：18

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