Celiac disease: A progress report

被引：37

作者：

Antonioli, DA

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Pathol, Boston, MA 02215 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

来源：

MODERN PATHOLOGY | 2003年 / 16卷 / 04期

关键词：

celiac disease; gluten-sensitive enteropathy; malabsorption;

D O I：

10.1097/01.MP.0000062997.16339.47

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Celiac disease (CD) has a wide range of clinical presentations and is being diagnosed with increasing frequency in patients in the 4th and 5th decades of life. The diagnosis of CD is confirmed by a combination of clinical, serological, and morphological findings associated with a response to a gluten-free diet. In small-bowel mucosal biopsy specimens, abnormalities range from minimal (increased villous intraepithelial lymphocytes only) to severe (complete villous blunting with crypt hyperplasia). Recognition of CD is important, because appropriate therapy of this condition will obviate the risk of its severe complications.

引用

页码：342 / 346

页数：5

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