Highly integrated surface potential sensors

被引:25
作者
George, M
Parak, WJ
Gaub, HE
机构
[1] Univ Munich, Inst Angew Phys, D-80799 Munich, Germany
[2] Univ Munich, Ctr Nanosci, D-80799 Munich, Germany
关键词
chemical imaging; surface potential sensor; spatial resolution; potential sensitivity; LAPS;
D O I
10.1016/S0925-4005(00)00506-2
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
For chemical imaging, surface potential sensors with multiple active sites are desirable. In the first part of this study, it will be described how simply by changing the geometry of established surface potential sensors, like (i) microelectrode arrays, (ii) electrolyte insulator-semiconductor (EIS) diode arrays and (iii) field-effect transistor (FET) arrays, devices with an enhanced integration density of active sites, called (i) light-addressable microelectrode arrays, (ii) the light-addressable potentiometric sensor (LAPS) and (iii) the field-effect-addressable potentiometric sensor (FAPS), can be designed. In the second part of this study, it will be discussed, especially in the case of the LAPS, whether this gain in integration density of active sites has to be paid with a loss in potential sensitivity. (C) 2000 Elsevier Science S.A. All rights reserved.
引用
收藏
页码:266 / 275
页数:10
相关论文
共 59 条
[1]  
ALEGRET S, 1993, SENSOR ACTUAT B-CHEM, V15, P453
[2]   THE DEVELOPMENT AND APPLICATION OF FET-BASED BIOSENSORS [J].
BERGVELD, P .
BIOSENSORS, 1986, 2 (01) :15-33
[3]   Characterization and optimization of microelectrode arrays for in vivo nerve signal recording and stimulation [J].
Blau, A ;
Ziegler, C ;
Heyer, M ;
Endres, F ;
Schwitzgebel, G ;
Matthies, T ;
Stieglitz, T ;
Meyer, JU ;
Gopel, W .
BIOSENSORS & BIOELECTRONICS, 1997, 12 (9-10) :883-892
[4]  
BOHM S, IN PRESS SENS ACTU B
[5]   COMBINED MEASUREMENT OF SURFACE-POTENTIAL AND ZETA POTENTIAL AT INSULATOR ELECTROLYTE INTERFACES [J].
BOUSSE, LJ ;
MOSTARSHED, S ;
HAFEMAN, D .
SENSORS AND ACTUATORS B-CHEMICAL, 1992, 10 (01) :67-71
[6]   DETECTION OF CELL-ACTIVITY VIA ISFET DEVICES - MODELING AND COMPUTER-SIMULATIONS [J].
CAMBIASO, A ;
GRATTAROLA, M ;
ARNALDI, G ;
MARTINOIA, S ;
MASSOBRIO, G .
SENSORS AND ACTUATORS B-CHEMICAL, 1990, 1 (1-6) :373-379
[7]   AN EXTRACELLULAR MICROELECTRODE ARRAY FOR MONITORING ELECTROGENIC CELLS IN CULTURE [J].
CONNOLLY, P ;
CLARK, P ;
CURTIS, ASG ;
DOW, JAT ;
WILKINSON, CDW .
BIOSENSORS & BIOELECTRONICS, 1990, 5 (03) :223-234
[8]   Multianalyte sensor for the simultaneous determination of glucose, L-lactate and uric acid based on a microelectrode array [J].
Frebel, H ;
Chemnitius, GC ;
Cammann, K ;
Kakerow, R ;
Rospert, M ;
Mokwa, W .
SENSORS AND ACTUATORS B-CHEMICAL, 1997, 43 (1-3) :87-93
[9]   A NEURON-SILICON JUNCTION - A RETZIUS CELL OF THE LEECH ON AN INSULATED-GATE FIELD-EFFECT TRANSISTOR [J].
FROMHERZ, P ;
OFFENHAUSSER, A ;
VETTER, T ;
WEIS, J .
SCIENCE, 1991, 252 (5010) :1290-1293
[10]  
GEORGE M, UNPUB SENSORS ACTU A