The role of the T-pilus in horizontal gene transfer and tumorigenesis

被引：29

作者：

Kado, CI ^{[1
]}

机构：

[1] Univ Calif Davis, Davis Crown Gall Grp, Davis, CA 95616 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 06期

关键词：

D O I：

10.1016/S1369-5274(00)00154-5

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The T-pilus is a flexuous filamentous appendage that is essential for Agrobacterium tumefaciens virulence. T-pilus subunits are derived from a VirB2-processing reaction that generates cyclized polypeptide subunits. The T-pilus filament has a diameter of 10 nm and contains a lumen approximately 2 nm in diameter. Biogenesis of the T-pilus requires all 11 VirB proteins, but not the VirD4 protein, which is used in conjugal plasmid transfer. VirB4 and VirB11 are two ATPases that may form homohexameric rings within the transport apparatus, which is composed of VirB6-10 proteins.

引用

页码：643 / 648

页数：6

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