Furanocoumarins from the root of Angelica dahurica

被引：111

作者：

Baek, NI

Ahn, EM

Kim, HY

Pauk, YD

机构：

[1] Kyung Hee Univ, Dept Life Sci, Suwon 449701, South Korea

[2] Kyung Hee Univ, Inst Life Sci, Suwon 449701, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2000年 / 23卷 / 05期

关键词：

Angelica dahurica; linear furanocoumarin; long-range coupling ((5)J); imperatorin; isoimperatorin; oxypeucedanin hydrate; oxypeucedanin hydrate-3 ''-butyl ether; knidilin;

D O I：

10.1007/BF02976574

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five furanocoumarins including a new one were isolated from the root of Angelica dahurica by repeated silica gel column chromatography. Their chemical structures were determined to be isoimperatorin (1), oxypeucedanin hydrate-3"-butyl ether (2), imperatorin (3), knidilin (4), and oxypeucedanin hydrate (5). This represents the first study in which the compound 2 has been isolated and identified. The long-range coupling ((5)J) in the H-1-NMR spectrum observed in the linear furanocoumarin skeleton was also investigated in detail.

引用

页码：467 / 470

页数：4

共 12 条

[1]

Baek NamIn, 2000, Korean Journal of Pharmacognosy, V31, P23

[2]

GU ZM, 1990, CHEM PHARM BULL, V38, P2498, DOI 10.1248/cpb.38.2498

[3] STEROIDS, CHROMONE AND COUMARINS FROM ANGELICA-OFFICINALIS [J].

HARKAR, S ;

RAZDAN, TK ;

WAIGHT, ES .

PHYTOCHEMISTRY, 1984, 23 (02) :419-426

[4] ON COUMARINS FROM THE FRUITS OF ANGELICA-PUBESCENS MAXIM [J].

HATA, K ;

NISHINO, T ;

HIRAI, Y ;

WADA, Y ;

KOZAWA, M .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1981, 101 (01) :67-71

[5]

KIM S H, 1992, Archives of Pharmacal Research (Seoul), V15, P73, DOI 10.1007/BF02973988

[6]

KOZAWA M, 1981, Shoyakugaku Zasshi, V35, P90

[7]

Lee CK., 1982, KOR J PHARMACOGN, V13, P10

[8]

PAVIA DL, 1996, INTRO SPECTROSCOPY, P203

[9] Coumarins of the roots of Angelica dahurica [J].

Qiao, SY ;

Yao, XS ;

Wang, ZY .

PLANTA MEDICA, 1996, 62 (06) :584-584

[10]

SASAKI H, 1982, CHEM PHARM BULL, V30, P3555

← 1 2 →