Conserved in structure but diverse in recognition

被引：5

作者：

Sun, PD ^{[1
]}

机构：

[1] NIAID, Struct Immunol Sect, NIH, Rockville, MD 20852 USA

来源：

STRUCTURE | 2003年 / 11卷 / 04期

关键词：

D O I：

10.1016/S0969-2126(03)00053-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The crystal structure of BMP7 in complex with the type 11 activin receptor shows a different receptor binding site on the ligand compared to that observed in the TGF-beta3 and receptor complex. The result highlights the potential diversity in ligand recognition among members of the TGF-beta superfamily.

引用

页码：362 / 363

页数：2

共 3 条

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[2]

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NATURE STRUCTURAL BIOLOGY, 2002, 9 (03) :203-208

[3]

Kirsch T, 2000, NAT STRUCT BIOL, V7, P492

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