Severe Acute Respiratory Syndrome and Coronavirus

被引：47

作者：

Hui, David S. C. ^{[1
,3
]}

Chan, Paul K. S. ^{[2
,4
]}

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Div Resp Med, Stanley Ho Ctr Emerging Infect Dis, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Microbiol, Shatin, Hong Kong, Peoples R China

[3] Chinese Univ Hong Kong, Div Resp Med, Stanley Ho Ctr Emerging Infect Dis, Shatin, Hong Kong, Peoples R China

[4] Chinese Univ Hong Kong, Dept Microbiol, Shatin, Hong Kong, Peoples R China

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2010年 / 24卷 / 03期

关键词：

SARS; Clinical features; Pathogenesis; Treatment; Outcome; SARS-ASSOCIATED CORONAVIRUS; ANGIOTENSIN-CONVERTING ENZYME-2; COMMUNITY-ACQUIRED PNEUMONIA; CRITICALLY-ILL PATIENTS; QUALITY-OF-LIFE; HONG-KONG; SPIKE PROTEIN; PULMONARY-FUNCTION; CLINICAL-FEATURES; INTERFERON-BETA;

D O I：

10.1016/j.idc.2010.04.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Severe acute respiratory syndrome (SARS) is a highly infectious disease with a significant morbidity and mortality. Respiratory failure is the major complication, and patients may progress to acute respiratory distress syndrome. Health care workers are particularly vulnerable to SARS. SARS has the potential of being converted from droplet to airborne transmission. There is currently no proven effective treatment of SARS, so early recognition, isolation, and stringent infection control are the key to controlling this highly contagious disease. Horseshoe bats are implicated in the emergence of novel coronavirus infection in humans. Further studies are needed to examine host genetic markers that may predict clinical outcome.

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收藏

页码：619 / +

页数：21

相关论文

共 169 条

[1] Nitric oxide inhibits the replication cycle of severe acute respiratory syndrome coronavirus [J].

Åkerström, S ;

Mousavi-Jazi, M ;

Klingström, J ;

Leijon, M ;

Lundkvist, Å ;

Mirazimi, A .

JOURNAL OF VIROLOGY, 2005, 79 (03) :1966-1969

[2] Coronavirus main proteinase (3CLpro) structure:: Basis for design of anti-SARS drugs [J].

Anand, K ;

Ziebuhr, J ;

Wadhwani, P ;

Mesters, JR ;

Hilgenfeld, R .

SCIENCE, 2003, 300 (5626) :1763-1767

[3] Mechanisms of action of intravenous immune serum globulin in autoimmune and inflammatory diseases [J].

Ballow, M .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 100 (02) :151-157

[4] Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice [J].

Bisht, H ;

Roberts, A ;

Vogel, L ;

Bukreyev, A ;

Collins, PL ;

Murphy, BR ;

Subbarao, K ;

Moss, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (17) :6641-6646

[5] Children hospitalized with severe acute respiratory syndrome-related illness in Toronto [J].

Bitnun, A ;

Allen, U ;

Heurter, H ;

King, SM ;

Opavsky, MA ;

Ford-Jones, EL ;

Matlow, A ;

Kitai, I ;

Tellier, R ;

Richardson, S ;

Manson, D ;

Babyn, P ;

Read, S .

PEDIATRICS, 2003, 112 (04) :E261-E268

[6] Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area [J].

Booth, CM ;

Matukas, LM ;

Tomlinson, GA ;

Rachlis, AR ;

Rose, DB ;

Dwosh, HA ;

Walmsley, SL ;

Mazzulli, T ;

Avendano, M ;

Derkach, P ;

Ephtimios, IE ;

Kitai, I ;

Mederski, BD ;

Shadowitz, SB ;

Gold, WL ;

Hawryluck, LA ;

Rea, E ;

Chenkin, JS ;

Cescon, DW ;

Poutanen, SM ;

Detsky, AS .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (21) :2801-2809

[7] Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units [J].

Booth, TF ;

Kournikakis, B ;

Bastien, N ;

Ho, J ;

Kobasa, D ;

Stadnyk, L ;

Li, Y ;

Spence, M ;

Paton, S ;

Henry, B ;

Mederski, B ;

White, D ;

Low, DE ;

McGeer, A ;

Simor, A ;

Vearncombe, M ;

Downey, J ;

Jamieson, FB ;

Tang, P ;

Plummer, F .

JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (09) :1472-1477

[8] Severe acute respiratory syndrome coroavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides [J].

Bosch, BJ ;

Martina, BEE ;

van der Zee, R ;

Lepault, J ;

Haijema, BJ ;

Versluis, C ;

Heck, AJR ;

de Groot, R ;

Osterhaus, ADME ;

Rottier, PJM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (22) :8455-8460

[9] Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS [J].

Bukreyev, A ;

Lamirande, EW ;

Buchholz, UJ ;

Vogel, LN ;

Elkins, WR ;

St Claire, M ;

Murphy, BR ;

Subbarao, K ;

Collins, PL .

LANCET, 2004, 363 (9427) :2122-2127

[10] ACE2, a new regulator of the renin-angiotensin system [J].

Burrell, LM ;

Johnston, CI ;

Tikellis, C ;

Cooper, ME .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2004, 15 (04) :166-169

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