Histological substrate of human atrial fibrillation

被引:48
作者
Chimenti, Cristina [1 ,2 ]
Russo, Matteo A. [3 ,4 ]
Carpi, Angelo [5 ]
Frustaci, Andrea [1 ,2 ]
机构
[1] Univ Roma La Sapienza, Cardiovasc & Resp Sci Dept, I-00161 Rome, Italy
[2] IRCCS L Spallanzani, Cellular & Mol Cardiol Lab, Rome, Italy
[3] Univ Roma La Sapienza, Dept Expt Med, I-00161 Rome, Italy
[4] IRCCS San Raffaele La Pisana, Rome, Italy
[5] Univ Pisa, Dept Reprod & Ageing, Pisa, Italy
关键词
Atrial fibrillation; Myocardial disease; Pathology; Atrial biopsy; OF-FUNCTION MUTATION; DILATED CARDIOMYOPATHY; THYROID-HORMONE; HEART-FAILURE; RISK-FACTORS; DISEASE; PREVALENCE; HYPERTENSION; PREDICTORS; FIBROSIS;
D O I
10.1016/j.biopha.2009.09.017
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
100103 [病原生物学]; 100218 [急诊医学];
摘要
Histologic and ultrastructural examination of atrial tissue regarding the main entities responsible of human atrial fibrillation, is reported. The pathologic changes deriving from various disorders, like degenerative, inflammatory, ischemic diseases as well as from cardiac aging and hormonal imbalance are analysed. Structural changes associated with lone atrial fibrillation and investigated by atrial biopsy are also described, as being able to provide useful information on the disease's etiology, prognosis and treatment. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:177 / 183
页数:7
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