Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms

被引：133

作者：

Tang, Guo-Yi ^{[1
]}

Meng, Xiao ^{[1
]}

Li, Ya ^{[1
]}

Zhao, Cai-Ning ^{[1
]}

Liu, Qing ^{[1
]}

Li, Hua-Bin ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, South China Sea Bioresource Exploitat & Utilizat, Guangzhou 510006, Guangdong, Peoples R China

来源：

NUTRIENTS | 2017年 / 9卷 / 08期

基金：

中国国家自然科学基金;

关键词：

cardiovascular disease; vegetable; bioactive component; effect; mechanism; TOTAL PHENOLIC CONTENTS; AMBULATORY BLOOD-PRESSURE; FOCAL CEREBRAL-ISCHEMIA; CORONARY-HEART-DISEASE; APOE-DEFICIENT MICE; ANTIOXIDANT CAPACITIES; ENDOTHELIAL FUNCTION; LIPID PROFILE; IN-VITRO; DIOSCOREA-ZINGIBERENSIS;

D O I：

10.3390/nu9080857

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Epidemiological studies have shown that vegetable consumption is inversely related to the risk of cardiovascular diseases. Moreover, research has indicated that many vegetables like potatoes, soybeans, sesame, tomatoes, dioscorea, onions, celery, broccoli, lettuce and asparagus showed great potential in preventing and treating cardiovascular diseases, and vitamins, essential elements, dietary fibers, botanic proteins and phytochemicals were bioactive components. The cardioprotective effects of vegetables might involve antioxidation; anti-inflammation; anti-platelet; regulating blood pressure, blood glucose, and lipid profile; attenuating myocardial damage; and modulating relevant enzyme activities, gene expression, and signaling pathways as well as some other biomarkers associated to cardiovascular diseases. In addition, several vegetables and their bioactive components have been proven to protect against cardiovascular diseases in clinical trials. In this review, we analyze and summarize the effects of vegetables on cardiovascular diseases based on epidemiological studies, experimental research, and clinical trials, which are significant to the application of vegetables in prevention and treatment of cardiovascular diseases.

引用

页数：25

共 158 条

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