Measurement of optical transport properties of normal and malignant human breast tissue

被引：148

作者：

Ghosh, N ^{[1
]}

Mohanty, SK ^{[1
]}

Majumder, SK ^{[1
]}

Gupta, PK ^{[1
]}

机构：

[1] Ctr Adv Technol, Biomed Applicat Sect, Indore 452013, India

来源：

APPLIED OPTICS | 2001年 / 40卷 / 01期

关键词：

D O I：

10.1364/AO.40.000176

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We report measurement of optical transport parameters of normal and malignant (ductal carcinoma) human breast tissue. A spatially resolved steady-state diffuse reflectance technique was used for measurement of the reduced scattering coefficient (mu (s)') and the absorption coefficient (mu (a)) Of the tissue. The anisotropy parameter of scattering (g) was estimated by goniophotometric measurements of the scattering phase function. The values of mu (s)' and mu (a)' for malignant breast tissue were observed to be larger than those for normal breast tissue over the wavelength region investigated (450-650 nm). Further, by using both the diffuse reflectance and the goniophotometric measurements, we estimated the Mie equivalent average radius of tissue scatterers to be larger in malignant tissue than in normal tissue. (C) 2001 Optical Society of America OCIS codes: 170.0170, 170.6510, 170.7050, 170.3660.

引用

页码：176 / 184

页数：9

共 23 条

[1] In vivo local determination of tissue optical properties:: applications to human brain [J].

Bevilacqua, F ;

Piguet, D ;

Marquet, P ;

Gross, JD ;

Tromberg, BJ ;

Depeursinge, C .

APPLIED OPTICS, 1999, 38 (22) :4939-4950

[2]

Bohren C. F., 1998, ABSORPTION SCATTERIN

[3] Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods [J].

Fantini, S ;

Walker, SA ;

Franceschini, MA ;

Kaschke, M ;

Schlag, PM ;

Moesta, KT .

APPLIED OPTICS, 1998, 37 (10) :1982-1989

[4] A DIFFUSION-THEORY MODEL OF SPATIALLY RESOLVED, STEADY-STATE DIFFUSE REFLECTANCE FOR THE NONINVASIVE DETERMINATION OF TISSUE OPTICAL-PROPERTIES INVIVO [J].

FARRELL, TJ ;

PATTERSON, MS ;

WILSON, B .

MEDICAL PHYSICS, 1992, 19 (04) :879-888

[5] SCATTERING AND ABSORPTION OF TURBID MATERIALS DETERMINED FROM REFLECTION MEASUREMENTS .2. MEASURING METHOD AND CALIBRATION [J].

GROENHUIS, RAJ ;

TENBOSCH, JJ ;

FERWERDA, HA .

APPLIED OPTICS, 1983, 22 (16) :2463-2467

[6] SCATTERING AND ABSORPTION OF TURBID MATERIALS DETERMINED FROM REFLECTION MEASUREMENTS .1. THEORY [J].

GROENHUIS, RAJ ;

FERWERDA, HA ;

TENBOSCH, JJ .

APPLIED OPTICS, 1983, 22 (16) :2456-2462

[7] BOUNDARY-CONDITIONS FOR THE DIFFUSION EQUATION IN RADIATIVE-TRANSFER [J].

HASKELL, RC ;

SVAASAND, LO ;

TSAY, TT ;

FENG, TC ;

MCADAMS, MS ;

TROMBERG, BJ .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1994, 11 (10) :2727-2741

[8] Three-dimensional diffuse optical mammography with ultrasound localization in a human subject [J].

Holboke, MJ ;

Tromberg, BJ ;

Li, X ;

Shah, N ;

Fishkin, J ;

Kidney, D ;

Butler, J ;

Chance, B ;

Yodh, AG .

JOURNAL OF BIOMEDICAL OPTICS, 2000, 5 (02) :237-247

[9]

Ishimaru A., 1978, WAVE PROPAGATION SCA, P175

[10] Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium [J].

Kienle, A ;

Patterson, MS .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1997, 14 (01) :246-254

← 1 2 3 →