Aza-Baylis-Hillman reaction of β-substituted activated olerins with N-tosyl imines

被引：41

作者：

Shi, YL ^{[1
]}

Xu, YM ^{[1
]}

Shi, M ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2004年 / 346卷 / 9-10期

关键词：

aza-Baylis-Hillman reaction; enones; Lewis base catalyst; organic catalysis; phosphanes; N-tosyl imines;

D O I：

10.1002/adsc.200404045

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Aza-Baylis-Hillman reactions of P-substituted activated olefins such as crotonaldehyde, (E)propenyl phenyl ketone, hex-2-enal or pent-3-en-2-one with N-tosyl imines can be carried out for the first time in the presence of tertiary phosphine Lewis bases such as PPh2Me or PPhMe2 to give the corresponding Baylis-Hillman adducts in moderate to good yields under mild reaction conditions.

引用

页码：1220 / 1230

页数：11

共 35 条

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