Phenomena are presented whereby the performance of a dimethyl ether fuel cell (DDFC) at 80 degreesC is much lower when a Pt-Ru catalyst is used on the anode than when a Pt catalyst is used, in contrast to the higher performance achieved using a Pt-Ru catalyst over a Pt catalyst in direct methanol fuel cells (DMFC). The DDFC performance achieved using a Pt-RU catalyst increases with temperature and exceeds that using a Pt catalyst at temperatures over 100 degreesC. After high-temperature operation, the performance of DDFC using a Pt-RU catalyst at 80 degreesC is improved. By supplying sufficient steam before operation, the performance of DDFC using a Pt-RU catalyst at 80 degreesC is also found to improve. Before and during operation, more steam is needed for stable operation of the DDFC using a Pt-RU catalyst at 80 degreesC than using a Pt catalyst. (C) 2004 Wiley Periodicals, Inc.