Heritable connective tissue disorders in cervical artery dissections: A prospective study

被引：78

作者：

Schievink, WI

Wijdicks, EFM

Michels, VV

Vockley, J

Godfrey, M

机构：

[1] Mayo Clin & Mayo Fdn, Dept Neurol Surg, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, Dept Med Genet, Rochester, MN 55905 USA

[3] Univ Nebraska, Med Ctr, Dept Pediat, Omaha, NE USA

[4] Univ Nebraska, Med Ctr, Munroe Ctr Human Genet, Omaha, NE USA

来源：

NEUROLOGY | 1998年 / 50卷 / 04期

关键词：

D O I：

10.1212/WNL.50.4.1166

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We prospectively evaluated 15 consecutive patients with spontaneous cervical artery dissections. Three patients (20%) had a heritable connective tissue disorder, each with a unique phenotype. None of these patients met the criteria of any of the named syndromes, and collagen and fibrillin analyses were normal. Heritable connective tissue disorders are common among patients with spontaneous cervical artery dissections, but, despite intensive investigations, the type of disorder usually cannot be identified. The underlying arteriopathy in cervical artery dissections is likely to be heterogeneous.

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页码：1166 / 1169

页数：4

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