First cross-coupling reactions of arylmagnesates:: a convenient access to heteroarylquinolines

被引：40

作者：

Dumouchel, S ^{[1
]}

Mongin, F ^{[1
]}

Trécourt, F ^{[1
]}

Quéguiner, G ^{[1
]}

机构：

[1] IRCOF, Lab Chim Organ Fine & Heterocycl, UMR 6014, F-76131 Mont St Aignan, France

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 19期

关键词：

cross-coupling; ate complexes; magnesium; quinoline;

D O I：

10.1016/S0040-4039(03)00786-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-, 3- and 4-Bromoquinolines were converted to the corresponding lithium tri(quinolyl)magnesates at -10degreesC on treatment with Bu3MgLi in THF. The resulting organomagnesium derivatives were involved in catalyzed cross-coupling reactions with heteroaryl bromides and chlorides to afford functionalized quinolines. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3877 / 3880

页数：4

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