High incidence of in-transit metastases after sentinel node biopsy in patients with melanoma

被引:59
作者
Estourgie, SH [1 ]
Nieweg, OE [1 ]
Kroon, BBR [1 ]
机构
[1] Antoni Van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Surg, NL-1066 CX Amsterdam, Netherlands
关键词
D O I
10.1002/bjs.4692
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: The occurrence of in-transit metastases in patients with a tumour-positive sentinel node varies greatly between centres and it has been suggested that the incidence is high in this patient group. Methods: The incidence of in-transit metastases in 61 patients who had lymph node dissection because of a tumour-positive sentinel node was compared with that in 60 patients who had palpable nodal metastases dissected. Results: The incidence of in-transit metastases was 23 per cent in patients with a positive sentinel node and 8 per cent in those with palpable nodes (P = 0.027). Conclusion: Sentinel node biopsy was associated with a higher risk of in-transit metastases. This finding does not support the routine use of sentinel node biopsy in the management of melanoma.
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收藏
页码:1370 / 1371
页数:2
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