Allelic frequencies of twelve dinucleotide repeat marker loci on chromosome 13 in the normal Japanese population

被引：2

作者：

Yamane, Y

Nakamura, Y

Isomura, M

机构：

[1] Univ Tokyo, Inst Med Sci, Mol Med Lab, Minato Ku, Tokyo 108, Japan

[2] Japanese Fdn Canc Res, Ctr Canc Chemotherapy, Dept Human Genome Anal, Toshima Ku, Tokyo 170, Japan

来源：

JAPANESE JOURNAL OF HUMAN GENETICS | 1997年 / 42卷 / 04期

关键词：

microsatellite marker; allelic distribution; linkage analysis;

D O I：

10.1007/BF02767030

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

To establish a genotypic database for dinucleotide repeat marker loci in the Japanese population, we determined allelic frequencies of 12 such markers on chromosome 13 and compared them with data from Caucasians in the GDB archive. The average heterozygosity (79%) for the 12 loci was the same for the two populations. However, allelic distributions at two of the marker loci were quite different. These data will be useful for disease studies in the Japanese population that involve linkage or sibship-pair analyses, or association studies.

引用

页码：533 / 537

页数：5