Intravenous tPA in acute ischemic stroke related to internal carotid artery dissection

被引：77

作者：

Derex, L

Nighoghossian, N

Turjaman, F

Hermier, M

Honnorat, J

Neuschwander, P

Froment, JC

Trouillas, P

机构：

[1] Hop Neurol & Neurochirurg P Wertheimer, Serv Urgences Neurovasc, F-69003 Lyon, France

[2] Hop Neurol, Serv Neuroradiol, Lyon, France

来源：

NEUROLOGY | 2000年 / 54卷 / 11期

关键词：

internal carotid dissection; acute ischemic stroke; tissue plasminogen; thrombolytic therapy;

D O I：

10.1212/WNL.54.11.2159

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors describe the outcomes in 11 patients who had acute ischemic stroke related to internal carotid artery (ICA) dissection and were treated with IV tissue plasminogen activator (tPA). One symptomatic intracerebral hemorrhage occurred 36 hours after tPA was given. The mean day 90 modified Rankin Scale (m-RS) score was 2.4 (+/-1.6). No death was observed at 3 months. Four patients of 11 (36.4%) made an excellent recovery (day 90 m-RS score: 0 to 1). This study demonstrates the feasibility of IV thrombolysis with tPA (0.8 mg/kg) in ischemic stroke related to ICA dissection within the first 7 hours

引用

页码：2159 / 2161

页数：3

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