A new direct synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids in the presence of sodium borohydride

被引：17

作者：

Chiriac, CI ^{[1
]}

Tanasa, F ^{[1
]}

Onciu, M ^{[1
]}

机构：

[1] Petru Poni Inst Macromol Chem, Iasi 6600, Romania

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(03)00529-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cinnamic acids have been prepared in 59-86% yields by a new direct synthesis from aromatic aldehydes and aliphatic carboxylic acids in the presence of sodium borohydride and N-methyl-2-pyrrolidinone (NMP) as solvent, at reflux (185-190degreesC), for 9-12 hours. Without sodium borohydride, this reaction is not possible. (C) 2003 Published by Elsevier Science Ltd.

引用

页码：3579 / 3580

页数：2

共 11 条

[1] MEERWEIN REACTION IN AMINO ACID SYNTHESIS .1. ALPHA-BROMO-O-, M-, AND P-CHLOROHYDROCINNAMIC ACIDS AND CORRESPONDING CHLOROPHENYLALANINES - ALPHA-BROMO- AND ALPHA-CHLOROHYDROCINNAMAMIDE [J].