Preparation of biodegradable hollow nanocapsules by silica template method

被引：121

作者：

Itoh, Y ^{[1
]}

Matsusaki, M ^{[1
]}

Kida, T ^{[1
]}

Akashi, M ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Engn, Dept Mol Chem, Suita, Osaka 5650871, Japan

来源：

CHEMISTRY LETTERS | 2004年 / 33卷 / 12期

关键词：

D O I：

10.1246/cl.2004.1552

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biodegradable hollow nanocapsules were successfully prepared by a combination of layer-by-layer assembly and the silica template method. Ultrathin polymer films were constructed on the surface of the silica nanoparticles by layer-by-layer assembly of oppositely charged biodegradable polyelectrolytes, chitosan and dextran sulfate. The silica templates were easily removed from the ultrathin polymer film-coated nanoparticles by treatment with hydrofluoric acid solution to create hollow nanocapsules. The hollow shape of these biodegradable nanocapsules was confirmed by SEM observation.

引用

页码：1552 / 1553

页数：2

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