HLA-G polymorphisms: neutral evolution or novel function?

被引：69

作者：

Ober, C ^{[1
]}

Aldrich, CL ^{[1
]}

机构：

[1] Univ Chicago, Ctr Med Genet, Dept Obstet & Gynecol, Chicago, IL 60637 USA

来源：

JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1997年 / 36卷 / 1-2期

关键词：

HLA-G; polymorphisms; evolution; linkage disequilibrium;

D O I：

10.1016/S0165-0378(97)00062-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

HLA-G is a non-classical class Ib gene with many unusual features. Because of its unique expression pattern, which is primarily limited to fetal cells at the maternal fetal interface, this gene has gained the attention of many investigators. In this paper we review some of the novel features of HLA-G, with particular reference to polymorphic variants in the gene, and discuss the implications of these features for the potential function and evolutionary history of HLA-G. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：1 / 21

页数：21

共 53 条

[1] EVIDENCE FOR A POLYMORPHISM OF HLA-G GENE [J].

ALIZADEH, M ;

LEGRAS, C ;

SEMANA, G ;

LEBOUTEILLER, P ;

GENETET, B ;

FAUCHET, R .

HUMAN IMMUNOLOGY, 1993, 38 (03) :206-212

[2]

BEGOVICH AB, 1992, J IMMUNOL, V148, P249

[3] DETECTION OF MEMBRANE-BOUND HLA-G TRANSLATED PRODUCTS WITH A SPECIFIC MONOCLONAL-ANTIBODY [J].

BENSUSSAN, A ;

MANSUR, IG ;

MALLET, V ;

RODRIGUEZ, AM ;

GIRR, M ;

WEISS, EH ;

BREM, G ;

BOUMSELL, L ;

GLUCKMAN, E ;

DAUSSET, J ;

CAROSELLA, E ;

LEBOUTEILLER, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (22) :10292-10296

[4] Allelic diversity at the primate Mhc-G locus: Exon 3 bears stop codons in all Cercophitecinae sequences [J].

Castro, MJ ;

Morales, P ;

FernandezSoria, V ;

Suerez, B ;

Recio, MJ ;

Alvarez, M ;

MartinVilla, M ;

ArnaizVillena, A .

IMMUNOGENETICS, 1996, 43 (06) :327-336

[5] IN-SITU HYBRIDIZATION AND NORTHERN BLOT DEMONSTRATION OF HLA-G MESSENGER-RNA IN HUMAN TROPHOBLAST POPULATIONS BY LOCUS-SPECIFIC OLIGONUCLEOTIDE [J].

CHUMBLEY, G ;

KING, A ;

HOLMES, N ;

LOKE, YW .

HUMAN IMMUNOLOGY, 1993, 37 (01) :17-22

[6] GENERATION OF AN ANTIBODY TO HLA-G IN TRANSGENIC MICE AND DEMONSTRATION OF THE TISSUE REACTIVITY OF THIS ANTIBODY [J].

CHUMBLEY, G ;

KING, A ;

GARDNER, L ;

HOWLETT, S ;

HOMLES, N ;

LOKE, YW .

JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1994, 27 (03) :173-186

[7]

ELLIS SA, 1986, IMMUNOLOGY, V59, P595

[8]

ELLIS SA, 1990, J IMMUNOL, V144, P731

[9]

FLAHERTY L, 1990, CRIT REV IMMUNOL, V10, P131

[10]

FUJII T, 1994, J IMMUNOL, V153, P5516

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