Severe psychiatric problems in right hepatic lobe donors for living donor liver transplantation

被引:75
作者
Trotter, James F.
Hill-Callahan, Margaret M.
Gillespie, Brenda W.
Nielsen, Carrie A.
Saab, Sammy
Shrestha, Roshan
Talamantes, Michael M.
Weinrieb, Robert M.
机构
[1] Univ Colorado, Dept Surg, Denver, CO 80202 USA
[2] Univ Michigan, Dept Surg, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA
[4] Univ N Carolina, Dept Hepatol, Chapel Hill, NC 27515 USA
[5] Univ Calif Berkeley, Dept Med, Berkeley, CA 94720 USA
[6] Piedmont Hosp, Dept Transplant Serv, Atlanta, GA USA
[7] Univ Colorado, Dept Transplant Surg, Denver, CO 80202 USA
[8] Univ Penn, Dept Psychiat, Philadelphia, PA 19104 USA
关键词
transplantation; psychiatric; morbidity; liver;
D O I
10.1097/01.tp.0000263343.21714.3b
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
Background. The morbidity and mortality from donation of a right hepatic lobe for living donor liver transplantation (LDLT) is an important issue for this procedure. We report the prevalence of severe psychiatric postoperative complications from the Adult-to-Adult Living Donor Liver Transplantation Cohort study (A2ALL), which was established to define the risks and benefits of LDLT for donors and recipients. Methods. Severe psychiatric complications were evaluated in all donors from the A2ALL study who were evaluated between 1998 and February 2003. Results. Of the 392 donors, 16 (4.1%) had one or multiple psychiatric complications, including three severe psychiatric complications (suicide, accidental drug overdose, and suicide attempt). Conclusions. Despite extensive preoperative screening, some donors experience severe psychiatric complications, including suicide, after liver donation. Psychiatric assessment and monitoring of liver donors may help to understand and prevent such tragic events.
引用
收藏
页码:1506 / 1508
页数:3
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