Triad of exophthalmos, pretibial myxedema, and acropachy in a patient with Graves' disease

被引：25

作者：

Anderson, CK ^{[1
]}

Miller, OF ^{[1
]}

机构：

[1] Geisinger Med Ctr, Dept Dermatol, Danville, PA 17822 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2003年 / 48卷 / 06期

关键词：

D O I：

10.1067/mjd.2003.323

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Graves' disease is an autoimmune disorder of the thyroid gland with characteristic peripheral manifestations. The most common clinical findings include ophthahnopathy in 30% of patients, dermopathy (pretibial myxedema) in 4% of patients, and thyroid acropachy in 1% of patients. The triad of exophthalmos, pretibial myxedema, and acropachy Occurs in less than 1% of patients. We present a case of Graves' disease with the clinical triad of eye disease, dermopathy, and acropachy.

引用

页码：970 / 972

页数：3

共 26 条

[1]

Antonelli A, 1992, Clin Ter, V141, P63

[2] A GENOMIC POINT MUTATION IN THE EXTRACELLULAR DOMAIN OF THE THYROTROPIN RECEPTOR IN PATIENTS WITH GRAVES OPHTHALMOPATHY [J].

BAHN, RS ;

DUTTON, CM ;

HEUFELDER, AE ;

SARKAR, G .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 78 (02) :256-260

[3] Clinical features of Graves' ophthalmopathy in an incidence cohort [J].

Bartley, GB ;

Fatourechi, V ;

Kadrmas, EF ;

Jacobsen, SJ ;

Ilstrup, DM ;

Garrity, JA ;

Gorman, CA .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 1996, 121 (03) :284-290

[4]

BURCH HB, 1995, WERNER INBGARS THYRO, P536

[5] PENTOXIFYLLINE INHIBITS THE PROLIFERATION AND GLYCOSAMINOGLYCAN SYNTHESIS OF CULTURED FIBROBLASTS DERIVED FROM PATIENTS WITH GRAVES OPHTHALMOPATHY AND PRETIBIAL MYXEDEMA [J].

CHANG, CC ;

CHANG, TC ;

KAO, SCS ;

KUO, YF ;

CHIEN, LF .

ACTA ENDOCRINOLOGICA, 1993, 129 (04) :322-327

[6] OCTREOTIDE AND GRAVES OPHTHALMOPATHY AND PRETIBIAL MYXEDEMA [J].

CHANG, TC ;

KAO, SCS ;

HUANG, KM .

BRITISH MEDICAL JOURNAL, 1992, 304 (6820) :158-158

[7] TSH AND TSH RECEPTOR ANTIBODY-BINDING SITES IN FIBROBLASTS OF PRETIBIAL MYXEDEMA ARE RELATED TO THE EXTRACELLULAR DOMAIN OF ENTIRE TSH RECEPTOR [J].

CHANG, TC ;

WU, SL ;

HSIAO, YL ;

KUO, ST ;

CHIEN, LF ;

KUO, YF ;

CHANG, CC ;

CHANG, TJ .

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 1994, 71 (01) :113-120

[8] Lack of an association between alleles of interleukin-1 alpha and interleukin-1 receptor antagonist genes and Graves' disease in a North American Caucasian population [J].

Cuddihy, RM ;

Bahn, RS .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (12) :4476-4478

[9]

FATOURECHI V, 1994, MEDICINE, V73, P1

[10] Hypothyroidism [J].

Freeman, AG .

LANCET, 1997, 349 (9057) :1023-1024

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