Identification of a new HLA-B*78 allele in a Hispanic family

被引:4
作者
Gaidulis, L
Krausa, P
Schaub, B
Senitzer, D
机构
[1] City Hope Natl Med Ctr, Dept Hematol & Bone Marrow Transplantat, HLA Lab, Duarte, CA 91010 USA
[2] PE Biosyst, Mol Diagnost Grp, Foster City, CA USA
来源
TISSUE ANTIGENS | 2000年 / 56卷 / 02期
关键词
HLA-B*78 alleles; HLA-B sequence-B*7804; sequencing based typing;
D O I
10.1034/j.1399-0039.2000.560215.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A new B*78 variant, B*7804, was detected in three members of a Hispanic family. The novel B*78 sequence differs from B*78021 by two substitutions: T at nucleotide 527 (all other B*78s have A) and T at nucleotide 583 (all other B*78s have a C). Both nucleotide substitutions encode amino acid changes at codons 152 and 171, respectively.
引用
收藏
页码:184 / 187
页数:4
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