Subthalamic nucleus deep brain stimulation in Parkinson disease patients over age 70 years

被引：103

作者：

Russmann, H

Ghika, J

Villemure, JG

Robert, B

Bogousslavsky, J

Burkhard, PR

Vingerhoets, FJG

机构：

[1] Univ Hosp CHUV, Dept Neurol, Lausanne, Switzerland

[2] Univ Hosp CHUV, Dept Neurosurg, Lausanne, Switzerland

[3] Univ Hosp HUG, Dept Neurol, Geneva, Switzerland

来源：

NEUROLOGY | 2004年 / 63卷 / 10期

关键词：

D O I：

10.1212/01.WNL.0000144198.26309.D8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The effects of subthalamic nucleus deep brain stimulation were studied in 52 consecutive patients ( 13 over age 70, 15 under age 60, 24 age 60 to 70). All groups had improvement of motor fluctuations and dyskinesia. Patients over age 70 had worsening of Unified Parkinson's Disease Rating Scale motor scores on medication, despite less medication reduction. Their activities of daily living and axial subscores worsened, particularly in those with preoperative gait difficulties.

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页码：1952 / 1954

页数：3

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