Topoisomerase II and the response to antileukemic therapy

被引：24

作者：

Kaufmann, SH ^{[1
]}

Gore, SD ^{[1
]}

Miller, CB ^{[1
]}

Jones, RJ ^{[1
]}

Zwelling, LA ^{[1
]}

Schneider, E ^{[1
]}

Burke, PJ ^{[1
]}

Karp, JE ^{[1
]}

机构：

[1] Mayo Clin & Mayo Fdn, Div Oncol Res, Rochester, MN 55905 USA

来源：

LEUKEMIA & LYMPHOMA | 1998年 / 29卷 / 3-4期

关键词：

topoisomerase II; antileukemic therapy; response to therapy;

D O I：

10.3109/10428199809068560

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A number of recent studies have investigated the expression of topoisomerase TI in clinical leukemia specimens. Here we outline the rationale for these studies, identify potential pitfalls, summarize recent results, and discuss unanswered questions in this area.

引用

页码：217 / 237

页数：21

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