Stopping primary prophylaxis in HIV-1-infected patients at high risk of toxoplasma encephalitis

被引：49

作者：

Furrer, H ^{[1
]}

Opravil, M

Bernasconi, E

Telenti, A

Egger, M

机构：

[1] Univ Bern, Div Infect Dis, CH-3010 Bern, Switzerland

[2] Univ Zurich, Div Infect Dis, Zurich, Switzerland

[3] Cantonal Hosp Lugano, Div Internal Med, Lugano, Switzerland

[4] Univ Lausanne, Div Infect Dis, Lausanne, Switzerland

[5] Univ Bristol, Dept Social Med, Div Infect Dis, MRC,Hlth Serv Res Collaborat, Bristol, Avon, England

来源：

LANCET | 2000年 / 355卷 / 9222期

关键词：

D O I：

10.1016/S0140-6736(00)02407-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Discontinuation of primary prophylaxis against toxoplasma encephalitis was studied in 199 HIV-1-infected patients on antiretroviral combination treatment who had experienced a sustained increase in their CD4 count. During a follow-up of 272 person-years, no cases of toxoplasma encephalitis arose.

引用

页码：2217 / 2218

页数：2

共 5 条

[1]

[Anonymous], 1999, MMWR Recomm Rep, V48, P1

[2] LOW-DOSE TRIMETHOPRIM-SULFAMETHOXAZOLE PROPHYLAXIS FOR TOXOPLASMIC ENCEPHALITIS IN PATIENTS WITH AIDS [J].

CARR, A ;

TINDALL, B ;

BREW, BJ ;

MARRIOTT, DJ ;

HARKNESS, JL ;

PENNY, R ;

COOPER, DA .

ANNALS OF INTERNAL MEDICINE, 1992, 117 (02) :106-111

[3] Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study [J].

Egger, M ;

Hirschel, B ;

Francioli, P ;

Sudre, P ;

Wirz, M ;

Flepp, M ;

Rickenbach, M ;

Malinverni, R ;

Vernazza, P ;

Battegay, M ;

Bernasconi, E ;

Burgisser, P ;

Erb, P ;

Fierz, W ;

Grob, P ;

Gruninger, U ;

Jeannerod, L ;

Ledergerber, B ;

Luthy, R ;

Matter, L ;

Opravil, M ;

Paccaud, F ;

Perrin, L ;

Pichler, W ;

Piffaretti, GC ;

Rutschmann, O ;

Zanetti, G .

BMJ-BRITISH MEDICAL JOURNAL, 1997, 315 (7117) :1194-1199

[4] Discontinuation of primary prophylaxis against Pneumocystis carinii pneumonia in HIV-1-infected adults treated with combination antiretroviral therapy [J].

Furrer, H ;

Egger, M ;

Opravil, M ;

Bernasconi, E ;

Hirschel, B ;

Battegay, M ;

Telenti, A ;

Vernazza, PL ;

Rickenbach, M ;

Flepp, M ;

Malinverni, R .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (17) :1301-1306

[5] ONCE-WEEKLY ADMINISTRATION OF DAPSONE PYRIMETHAMINE VS AEROSOLIZED PENTAMIDINE AS COMBINED PROPHYLAXIS FOR PNEUMOCYSTIS-CARINII PNEUMONIA AND TOXOPLASMIC ENCEPHALITIS IN HUMAN IMMUNODEFICIENCY VIRUS-INFECTED PATIENTS [J].

OPRAVIL, M ;

HIRSCHEL, B ;

LAZZARIN, A ;

HEALD, A ;

PECHERE, M ;

RUTTIMANN, S ;

ITEN, A ;

VONOVERBECK, J ;

OERTLE, D ;

PRAZ, G ;

VUITTON, A ;

MAININI, F ;

LUTHY, R .

CLINICAL INFECTIOUS DISEASES, 1995, 20 (03) :531-541

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