Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe

被引：37

作者：

Fink, PJ ^{[1
]}

McMahan, CJ ^{[1
]}

机构：

[1] Univ Washington, Dept Immunol, Seattle, WA 98195 USA

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 11期

关键词：

D O I：

10.1016/S0167-5699(00)01734-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pamela Fink and Catherine McMahan discuss how B and T cells test for useful antigen receptors and weed out potentially harmful ones, with special attention paid to T-cell receptor revision, a newly described mechanism by which mature T cells can maintain self tolerance.

引用

页码：561 / 566

页数：6

共 45 条

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