An aetiological classification of birth defects for epidemiological research

被引:24
作者
Wellesley, D
Boyd, P
Dolk, H
Pattenden, S
机构
[1] Princess Anne Hosp, Wessex Clin Genet Serv, Southampton SO16 5YA, Hants, England
[2] Univ Oxford, CAROBB Natl Perinatal Epidemiol Unit, Oxford OX3 7LG, England
[3] Univ Ulster, Fac Life & Hlth Sci, Newtownabbey BT37 0QB, Antrim, North Ireland
[4] Univ London London Sch Hyg & Trop Med, Dept Publ Hlth & Policy, Environm Epidemiol Unit, London WC1E 7HT, England
关键词
D O I
10.1136/jmg.2004.023309
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Background: Congenital anomaly registers collect data on antenatally and postnatally detected anomalies for surveillance, research, and public health purposes. Each anomaly is coded using the International Statistical Classification of Diseases and Related Health Problems ( ICD- 9/ ICD- 10) based on body systems, allowing accurate comparisons between registers for individual anomalies. When commencing an environmental, epidemiological study, it became clear to us that there is no standard classification that takes aetiology into account. This paper describes a new classification for use in studies addressing aetiology. Method: A classification system was evolved and piloted using cases in a study of geographical variation in congenital anomaly prevalence. 1 Cases that were difficult to categorise were noted, and after discussion with a team of experts, the classification was adjusted accordingly. Results and conclusion: A robust, hierarchical method of classifying birth defects into eight categories has been produced, for use at source of data registration in conjunction with, but independent of, ICD coding.
引用
收藏
页码:54 / 57
页数:4
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