Thromboprophylaxis in the intensive care unit: Focus on medical-surgical patients

被引:56
作者
Cook, Deborah J. [1 ,2 ]
Crowther, Mark A. [1 ]
机构
[1] McMaster Univ, Dept Med, Hamilton, ON, Canada
[2] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
关键词
venous thromboembolism; prevention; critical illness; DEEP VENOUS THROMBOSIS; MOLECULAR-WEIGHT HEPARIN; FATAL PULMONARY-EMBOLISM; CRITICALLY-ILL PATIENTS; LOW-DOSE HEPARIN; VEIN THROMBOSIS; DALTEPARIN THROMBOPROPHYLAXIS; THROMBOEMBOLISM PROPHYLAXIS; PREVENTION; PREVALENCE;
D O I
10.1097/CCM.0b013e3181c9e344
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Critically ill patients in the medical-surgical intensive care unit are at high risk for deep venous thrombosis and pulmonary embolism, which comprise venous thromboembolism. Herein, we describe the prevalence, incidence, risk factors, clinical consequences, prophylaxis against venous thromboembolism in critically ill patients, and compliance with thromboprophylaxis. We focus primarily on medical-surgical intensive care unit patients, who represent the largest subgroup of critically ill patients. Despite the large and growing number of critically ill patents in our aging society, their high risk for venous thromboembolism, and the morbidity and mortality associated with this complication of critical illness, relatively few rigorous studies are available. Large, well-designed, randomized trials of thromboprophylaxis, powered to detect differences in patient-important outcomes, are required to advance our understanding and care of these vulnerable patients. Furthermore, because thromboprophylaxis is a common error of omission in hospitalized patients, redoubled efforts are needed to ensure that it is used in practice. (Crit Care Med 2010; 38[Suppl.]:S76-S82)
引用
收藏
页码:S76 / S82
页数:7
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