Copper-catalyzed anti-stereocontrolled ring opening of oxabicyclic alkenes with Grignard reagents

被引：67

作者：

Arrayás, RG ^{[1
]}

Cabrera, S ^{[1
]}

Carretero, JC ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Fac Ciencias, Dept Quim Organ, E-28049 Madrid, Spain

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 08期

关键词：

D O I：

10.1021/ol034283m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general copper-catalyzed procedure for the stereoselective ring opening of [2.2.1]-oxabicyclic alkenes with Grignard reagents is described. In the presence of catalytic amounts of CuCl/PPh3 the reaction occurs with very high or complete anti selectivity in all cases.

引用

页码：1333 / 1336

页数：4

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