High-frequency rTMS improves time perception in Parkinson disease

被引:48
作者
Koch, G
Oliveri, M
Brusa, L
Stanzione, P
Torriero, S
Caltagirone, C
机构
[1] Fdn Santa Lucia, IRCCS, Lab Neurol Clin & Comportamentale, I-00179 Rome, Italy
[2] Univ Roma Tor Vergata, Dipartimento Neurosci, Neurol Clin, Rome, Italy
[3] Univ Palermo, Dipartimento Psicol, I-90133 Palermo, Italy
关键词
D O I
10.1212/01.WNL.0000147336.19972.82
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Patients with Parkinson disease (PD) are impaired in time processing. The authors investigated the effects of high-frequency (5 Hz) repetitive transcranial magnetic stimulation (rTMS) in patients with PD performing a time reproduction task. The authors found significant improvement in time processing induced by rTMS when trains were applied over the right dorsolateral prefrontal cortex (DLPFC) but not over the supplementary motor area, suggesting that the circuit involving the basal ganglia and the DLPFC might constitute the neural network subserving time perception.
引用
收藏
页码:2405 / 2406
页数:2
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