Combination therapy with cyclosporine A and anti-TNF-α agents in the treatment of rheumatoid arthritis and concomitant hepatitis C virus infection

被引：27

作者：

Bellisai, Francesca ^{[1
]}

Giannitti, Chiara ^{[1
]}

Donvito, Alessandro ^{[1
]}

Galeazzi, Mauro ^{[1
]}

机构：

[1] Policlin Le Scotte, UOC Reumatol, Dipartimento Med Clin & Sci Immunol, I-53100 Siena, Italy

来源：

CLINICAL RHEUMATOLOGY | 2007年 / 26卷 / 07期

关键词：

anti-TNF-alpha; cyclosporine A; HCV; rheumatoid arthritis;

D O I：

10.1007/s10067-006-0412-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe two cases of rheumatoid arthritis (RA) patients and concomitant hepatitis C virus infection (HCV), treated with cyclosporine A (CsA) and anti-TNF-alpha agents. SGOT/SGPT and HCV-RNA serum levels remained unchanged longer than 1 year of treatment. No side effects were registered. We suggest that combination therapy with CsA and TNF-alpha blockers should be considered safe and well-tolerated in the treatment of HCV-positive RA patients.

引用

页码：1127 / 1129

页数：3

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