Redistribution of aquaporins in uterine epithelial cells at the time of implantation in the rat

被引：49

作者：

Lindsay, LA

Murphy, CR

机构：

[1] Univ Sydney, Dept Anat & Histol, Sch Med Sci, Sydney, NSW 2006, Australia

[2] Univ Sydney, Dept Anat & Histol, Inst Biomed Res, Sydney, NSW 2006, Australia

来源：

ACTA HISTOCHEMICA | 2004年 / 106卷 / 04期

关键词：

uterus; implantation; uterine luminal fluid; aquaporins;

D O I：

10.1016/j.acthis.2004.05.004

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The aim of this study was to investigate the presence of aquaporins 1, 4 and 5 in uterine epithetial. cells during the early stages of pregnancy in the rat. Immunofluorescent and immunogold techniques showed that there was a shift of aquaporin 5 to the apical surface of uterine epithetial. cells in the mesometrial. pole of the uterus at the time of implantation. This study also revealed the absence of aquaporin 4 in the rat uterus during early pregnancy. Aquaporin 1 was observed in stromal. blood vessels but there was no change in uterine epithelial, cells during early pregnancy. These results suggest that aquaporin 5 plays an important rote in the removal. of uterine luminal fluid at the time of implantation in the rat and may contribute to the antimesometrial positioning of the implanting blastocyst. (C) 2004 Elsevier GmbH. All rights reserved.

引用

页码：299 / 307

页数：9

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