Oxazoline mediated routes to a unique amino-acid, 4-amino-13-carboxy[2.2]paracyclophane, of planar chirality

被引：38

作者：

Marchand, A

Maxwell, A

Mootoo, B

Pelter, A

Reid, A

机构：

[1] Univ Coll Swansea, Dept Chem, Swansea SA2 8PP, W Glam, Wales

[2] Univ W Indies, Dept Chem, St Augustine, Trinidad Tobago

来源：

TETRAHEDRON | 2000年 / 56卷 / 37期

关键词：

4-amino-13-carboxy[2.2]paracyclophane; planar chirality; oxazolines; directing effects; potential catalysts;

D O I：

10.1016/S0040-4020(00)00644-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient syntheses leading to 4-amino-13-carboxy[2.2]paracyclophane and derivatives are described. Novel oxazolinyl[2.2]paracyclophanes are used as intermediates and the oxazolinyl and amide groups are shown to be strong psi-geminal directing groups. Compounds with potential as catalysts have been made. (C) 2000 Elsevier Science Ltd. All rights reserved.

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收藏

页码：7331 / 7338

页数：8

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