Generation of dynamic constitutional diversity and driven evolution in helical molecular strands under Lewis acid catalyzed component exchange

被引：80

作者：

Giuseppone, N ^{[1
]}

Schmitt, JL ^{[1
]}

Lehn, JM ^{[1
]}

机构：

[1] Inst Sci & Ingn Supramol, F-67083 Strasbourg, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 37期

关键词：

combinatorial chemistry; Lewis acids; molecular evolution; scandium; self-assembly;

D O I：

10.1002/anie.200460343

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A stir in the library: The efficient Sc(OTf)3-catalyzed transimination of helical oligo-hydrazone strands has been utilized to yield a highly diverse constitutional dynamic library through assembly, dissociation, and exchange of components. This library can subsequently undergo driven evolution in the presence of ZnII ions to express preferentially [2 × 2] gridlike arrays by component recombination.

引用

页码：4902 / 4906

页数：5

共 38 条

[1] Designed self-generation of an extended helical structure from an achiral polyheterocyclic strand [J].

Bassani, DM ;

Lehn, JM ;

Baum, G ;

Fenske, D .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (17) :1845-1847

[2]

BASSANI DM, 1997, ANGEW CHEM, V109, P2534

[3]

Berl V, 2001, CHEM-EUR J, V7, P2798, DOI 10.1002/1521-3765(20010702)7:13<2798::AID-CHEM2798>3.0.CO

[4]

2-L

[5]

Berl V, 2001, CHEM-EUR J, V7, P2810, DOI 10.1002/1521-3765(20010702)7:13<2810::AID-CHEM2810>3.0.CO

[6]

2-5

[7]

GIUSEPPONE N, UNPUB

[8]

Gong B, 2001, CHEM-EUR J, V7, P4336, DOI 10.1002/1521-3765(20011015)7:20<4336::AID-CHEM4336>3.0.CO

[9]

2-1

[10] MOLECULAR HELICITY - A GENERAL-APPROACH FOR HELICITY INDUCTION IN A POLYHETEROCYCLIC MOLECULAR STRAND [J].

HANAN, GS ;

LEHN, JM ;

KYRITSAKAS, N ;

FISCHER, J .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (07) :765-766

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