Poloxamers and poloxamines in nanoparticle engineering and experimental medicine

被引：329

作者：

Moghimi, SM ^{[1
]}

Hunter, AC ^{[1
]}

机构：

[1] Univ Brighton, Sch Pharm & Biomol Sci, Mol Targeting & Polymer Toxicol Grp, Brighton BN2 4GJ, E Sussex, England

来源：

TRENDS IN BIOTECHNOLOGY | 2000年 / 18卷 / 10期

关键词：

D O I：

10.1016/S0167-7799(00)01485-2

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Poloxamers and poloxamine nonionic surfactants have diverse applications in various biomedical fields ranging from drug delivery and medical imaging to management of vascular diseases and disorders. Although this is a progressive, rapidly advancing field in biotechnology, the future will depend on the recognition and rectification of a range of toxicity issues, which have to be addressed but have frequently been ignored until now.

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页码：412 / 420

页数：9

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