The click reaction in the luminescent probing of metal ions, and its implications on biolabeling techniques

被引:50
作者
Wolfbeis, Otto S. [1 ]
机构
[1] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-93040 Regensburg, Germany
关键词
analytical methods; cell assays; click chemistry; copper; fluorescent probes;
D O I
10.1002/anie.200604897
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Chemical Equation Presented) Copper concentrations at a click: The copper(I)-catalyzed Huisgen cycloaddition (the "click reaction") enables micromolar concentrations of physiologically active Cu+ ions to be sensed through photonic energy transfer (ET, see scheme), and offers great potential in terms of labeling methods. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2980 / 2982
页数:3
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