Identification of novel stereogeometrical features in beta-Ala residue

被引：13

作者：

Kishore, R

机构：

[1] Institute of Microbial Technology, Sector - 39- A

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 32期

关键词：

D O I：

10.1016/0040-4039(96)01174-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conformational investigations of beta - alanine containing peptides, 1 and 2, in solution as well as in crystalline state, have revealed the preferences for chirality induced stereogeometrical features which restricted conformational averaging in solution. Evidences for the influences of these conformational features on circular dichroism (CD) spectral behavior of a chiral Ala residue have been provided. Copyright (C) 1996 Elsevier Science Ltd.

引用

收藏

页码：5747 / 5750

页数：4

相关论文

共 12 条

[1]

BANUMATHI D, 1995, NAT S CELL MOL BIOPH, P53

[2] CRYSTAL-STRUCTURE OF N(BETA)-TERT-BUTYLOXYCARBONYL-BETA-ALANYL-L-ALANINE METHYLAMIDE, C12H23N3O4 [J].

BARDI, R ;

PIAZZESI, AM ;

CRISMA, M ;

TONIOLO, C ;

KISHORE, R .

ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 1993, 207 :290-292

[3] INTRAMOLECULAR HYDROGEN-BONDING IN DERIVATIVES OF BETA-ALANINE AND GAMMA-AMINO BUTYRIC-ACID - MODEL STUDIES FOR THE FOLDING OF UNNATURAL POLYPEPTIDE BACKBONES [J].

DADO, GP ;

GELLMAN, SH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (03) :1054-1062

[4] BETA-AMINO ACIDS - MAMMALIAN METABOLISM AND UTILITY AS ALPHA-AMINO-ACID ANALOGS [J].

GRIFFITH, OW .

ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :855-878

[5] CARNOSINE (BETA-ALANYL-L-HISTIDINE) [J].

ITOH, H ;

YAMANE, T ;

ASHIDA, T ;

KAKUDO, M .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1977, 33 (SEP15) :2959-2961

[6] CONFORMATION OF CYCLIC TETRAPEPTIDE L-SER(O-T-BU)-BETA-ALA-GLY-L-BETA-ASP(OME) CONTAINING A 14-MEMBERED RING [J].

KARLE, IL ;

HANDA, BK ;

HASSALL, CH .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1975, 31 (FEB15) :555-560

[7] BIOSYNTHESIS OF PEPTIDE ANTIBIOTICS [J].

KLEINKAUF, H ;

VONDOHREN, H .

ANNUAL REVIEW OF MICROBIOLOGY, 1987, 41 :259-289

[8] SOLVENT-DEPENDENT CONFORMATIONAL DISTRIBUTIONS OF SOME DIPEPTIDES [J].

MADISON, V ;

KOPPLE, KD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (15) :4855-4863

[9] BETA-ALANINE AND BETA-BENDS - X-RAY-DIFFRACTION STRUCTURES OF 3 LINEAR OLIGOPEPTIDES [J].

PAVONE, V ;

DIBLASIO, B ;

LOMBARDI, A ;

ISERNIA, C ;

PEDONE, C ;

BENEDETTI, E ;

VALLE, G ;

CRISMA, M ;

TONIOLO, C ;

KISHORE, R .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1992, (08) :1233-1237

[10] BETA-ALANINE CONTAINING CYCLIC-PEPTIDES WITH TURNED STRUCTURE - THE PSEUDO-TYPE-II BETA-TURN .6. [J].

PAVONE, V ;

LOMBARDI, A ;

SAVIANO, M ;

NASTRI, F ;

FATTORUSSO, R ;

MAGLIO, O ;

ISERNIA, C ;

PAOLILLO, L ;

PEDONE, C .

BIOPOLYMERS, 1994, 34 (11) :1517-1526