Insights into Adult Postlesional Language Cortical Plasticity Provided by Cerebral Blood Oxygen Level-Dependent Functional MR Imaging

被引：25

作者：

Pillai, J. J. ^{[1
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机构：

[1] Johns Hopkins Univ, Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, Div Neuroradiol, Baltimore, MD USA

来源：

AMERICAN JOURNAL OF NEURORADIOLOGY | 2010年 / 31卷 / 06期

关键词：

PRIMARY SOMATOSENSORY AREA; COMPLEX PARTIAL EPILEPSY; LOW-GRADE GLIOMAS; RAT MOTOR CORTEX; BRAIN PLASTICITY; HORIZONTAL CONNECTIONS; SURGICAL RESECTION; RIGHT-HEMISPHERE; APHASIA; RECOVERY;

D O I：

10.3174/ajnr.A1896

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

BOLD fMRI has provided new insights into postlesional brain language plasticity by providing a noninvasive in vivo approach to evaluate longitudinal changes in brain cortical activation during performance of language tasks. Specifically, BOLD fMRI has provided the opportunity to investigate not only changes in eloquent language cortex resulting from different types of brain pathology such as brain tumors, stroke, and epilepsy but also changes in eloquent language cortex occurring as a result of actual surgical resection of diseased but, nevertheless, partially functional tissue. In addition to reviewing the literature relating to stroke and epilepsy-related language plasticity as well as the more intriguing phenomenon of postsurgical plasticity in the setting of brain tumors, 2 unusual cases illustrating this latter manifestation of language plasticity are briefly described in this review article.

引用

页码：990 / 996

页数：7

共 60 条

[1]

Bates E., 2001, Handbook of developmental cognitive neuroscience

[2] Post-lesional cerebral reorganisation:: Evidence from functional neuroimaging and transcranial magnetic stimulation [J].