Torsades de pointes associated with intravenous haloperidol in critically ill patients

被引：155

作者：

Sharma, ND

Rosman, HS

Padhi, ID

Tisdale, JE

机构：

[1] Henry Ford Hosp, Dept Internal Med, Div Cardiovasc Med, Detroit, MI 48202 USA

[2] Henry Ford Hosp, Dept Pharm Serv, Detroit, MI 48202 USA

[3] Wayne State Univ, Coll Pharm, Detroit, MI 48202 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1998年 / 81卷 / 02期

关键词：

D O I：

10.1016/S0002-9149(97)00888-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this retrospective case-control study, 8 of 223 consecutive patients (3.6%) treated with intravenous haloperidol developed torsades de pointes, and were compared with 41 patients randomly selected as controls. The likelihood of torsades de pointes associated with intravenous haloperidol is significantly greater in patients receiving ≤35 mg over 24 hours or in those with a QTc interval of >500 ms, or both.

引用

页码：238 / 240

页数：3

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