Desymmetrization of meso-dialdehydes with optically active cyclopentadienyldialkoxyallyltitanium complexes

被引:19
作者
BouzBouz, S [1 ]
Popkin, ME [1 ]
Cossy, J [1 ]
机构
[1] Ecole Super Phys & Chim Ind, Chim Organ Lab, CNRS, F-75231 Paris 05, France
关键词
D O I
10.1021/ol0057434
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Optically active cyclopentadienyldialkoxyallyltitanium complexes have been employed for the desymmetrization of meso-dialdehydes. Allylation of these dialdehydes and subsequent oxidation afford chiral lactones with good diastereoselectivity and excellent enantioselectivity.
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页码:3449 / 3451
页数:3
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