Selective attachment and release of a chemotherapeutic agent from the interior of a protein cage architecture

被引：136

作者：

Flenniken, ML

Liepold, LO

Crowley, BE

Willits, DA

Young, MJ

Douglas, T

机构：

[1] Montana State Univ, Dept Chem & Biochem, Bozeman, MT 59717 USA

[2] Montana State Univ, Dept Microbiol, Bozeman, MT 59717 USA

[3] Montana State Univ, Dept Plant Sci, Bozeman, MT 59717 USA

[4] Montana State Univ, Ctr Bioinspired Nanomat, Bozeman, MT 59717 USA

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 04期

关键词：

D O I：

10.1039/b413435d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The antitumor agent doxorubicin was covalently bound and selectively released in a pH dependent manner from the interior surface of a genetically modified small heat shock protein (Hsp) cage.

引用

页码：447 / 449

页数：3

共 21 条

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