Diagnostic testing and interpretation of tests for autoimmunity

被引:100
作者
Castro, Christine [1 ]
Gourley, Mark [1 ]
机构
[1] NIAMSD, NIH, Bethesda, MD 20892 USA
关键词
Autoimmune; disease; laboratory; inflammatory markers; evaluation; rheumatic; serologies; flow cytometry; HLA; organ specific; ANTIPHOSPHOLIPID SYNDROME; HEMOLYTIC-ANEMIA;
D O I
10.1016/j.jaci.2009.09.041
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Laboratory testing is of great value when evaluating a patient with a suspected autoimmune disease. The results can confirm a diagnosis, estimate disease severity, aid in assessing prognosis and are useful for following disease activity. Components of the laboratory examination include a complete blood count with differential, a comprehensive metabolic panel, measurement of inflammatory markers and autoantibodies, and flow cytometry. This chapter discusses these components and includes a discussion about organ-specific immunologic diseases for which immunologic laboratory testing is used. Comprehensive laboratory evaluation of a suspected autoimmune illness in conjunction with a thorough clinical evaluation provides a better understanding of a patient's immunologic disease. (J Allergy Clin Immunol 2010;125:S238-47.)
引用
收藏
页码:S238 / S247
页数:10
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