Base deficit in immediate postoperative period of coronary surgery with cardiopulmonary bypass and length of stay in intensive care unit

被引:18
作者
Hugot, P
Sicsic, JC
Schaffuser, A
Sellin, M
Corbineau, H
Chaperon, J
Ecoffey, C
机构
[1] Univ Rennes 1, CHU Pontchaillou, Dept Anesthesiol & Intens Care, F-35033 Rennes 9, France
[2] Univ Rennes 1, CHU Pontchaillou, Dept Cardiac Surg, F-35033 Rennes, France
[3] Univ Rennes 1, CHU Pontchaillou, Dept Epidemiol, F-35033 Rennes 9, France
关键词
cardiac surgery; coronary surgery; cardiopulmonary bypass; acid-base balance : base deficit;
D O I
10.1007/s00134-002-1587-9
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Objective: To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. Design and setting: Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospital. Patients: 185 consecutive patients. Interventions: Coronary artery bypass graft with cardiopulmonary by pass. Measurements and results: Thirty variables were determined during the pre-, intra-, and postoperative periods; a statistical univariate analysis was performed differentiating patients whose length of stay in the ICU was 2 days or less and those whose stay was more than 2 days. Secondly, a logistic regression model was performed on the variables shown to have a statistically significant difference in univariate analysis, with determination of the odd ratio. Fourteen variables had a statistically significant difference in univariate analysis and three of them highlighted by the logistic regression model: administration of catecholamines, base deficit value in the 1 st h postoperatively, and age with odd ratios, respectively, of 3.15, 1.51, and 1.07). Conclusions: The value of base deficit measured during the I st h after coronary surgery for cardiopulmonary bypass is correlated with the length of stay in ICU.
引用
收藏
页码:257 / 261
页数:5
相关论文
共 20 条
[1]   Base deficit after major trauma directly relates to neutrophil CD11 b expression: A proposed mechanism of shock-induced organ injury [J].
Botha, AJ ;
Moore, FA ;
Moore, EE ;
Peterson, VM ;
Goode, AW .
INTENSIVE CARE MEDICINE, 1997, 23 (05) :504-509
[2]   COMPARISON OF CLINICAL INFORMATION GAINED FROM ROUTINE BLOOD-GAS ANALYSIS AND FROM GASTRIC TONOMETRY FOR INTRAMURAL PH [J].
BOYD, O ;
MACKAY, CJ ;
LAMB, G ;
BLAND, JM ;
GROUNDS, RM ;
BENNETT, ED .
LANCET, 1993, 341 (8838) :142-146
[3]   BASE DEFICIT AS A GUIDE TO VOLUME RESUSCITATION [J].
DAVIS, JW ;
SHACKFORD, SR ;
MACKERSIE, RC ;
HOYT, DB .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1988, 28 (10) :1464-1467
[4]   THE RELATIONSHIP OF BASE DEFICIT TO LACTATE IN PORCINE HEMORRHAGIC-SHOCK AND RESUSCITATION [J].
DAVIS, JW .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1994, 36 (02) :168-172
[5]   Admission base deficit predicts transfusion requirements and risk of complications [J].
Davis, JW ;
Parks, SN ;
Kaups, KL ;
Gladen, HE ;
ODonnellNicol, S .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1996, 41 (05) :769-774
[6]  
DAVIS JW, 1991, SURG GYNECOL OBSTET, V173, P473
[7]   OXYGEN DEBT AND METABOLIC ACIDEMIA AS QUANTITATIVE PREDICTORS OF MORTALITY AND THE SEVERITY OF THE ISCHEMIC INSULT IN HEMORRHAGIC-SHOCK [J].
DUNHAM, CM ;
SIEGEL, JH ;
WEIRETER, L ;
FABIAN, M ;
GOODARZI, S ;
GUADALUPI, P ;
GETTINGS, L ;
LINBERG, SE ;
VARY, TC .
CRITICAL CARE MEDICINE, 1991, 19 (02) :231-243
[8]  
JONATHAN H, 1999, CRIT CARE MED, V27, P2142
[9]   Role of pump prime in the etiology and pathogenesis of cardiopulmonary bypass-associated acidosis [J].
Liskaser, FJ ;
Bellomo, R ;
Hayhoe, M ;
Story, D ;
Poustie, S ;
Smith, B ;
Letis, A ;
Bennett, M .
ANESTHESIOLOGY, 2000, 93 (05) :1170-1173
[10]   Determinants of duration of ICU stay after coronary artery bypass graft surgery [J].
Michalopoulos, A ;
Tzelepis, G ;
Pavlides, G ;
Kriaras, J ;
Dafni, U ;
Geroulanos, S .
BRITISH JOURNAL OF ANAESTHESIA, 1996, 77 (02) :208-212