Prospective outcomes evaluation after decompression with or without instrumented fusion for lumbar stenosis and degenerative Grade I spondylolisthesis

被引:138
作者
Ghogawala, Z
Benzel, EC
Amin-Hanjani, S
Barker, FG
Harrington, JF
Magge, SN
Strugar, J
Couman, JVCE
Borges, LF
机构
[1] Yale Univ, Dept Neurosurg, Greenwich Hosp, Sch Med, Greenwich, CT 06830 USA
[2] Cleveland Clin Fdn, Dept Neurosurg, Cleveland, OH 44195 USA
[3] Univ Illinois, Dept Neurosurg, Chicago, IL 60680 USA
[4] Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA 02114 USA
[5] Lahey Clin Fdn, Dept Neurosurg, Burlington, MA USA
[6] Rhode Isl Hosp, Dept Neurosurg, Providence, RI 02903 USA
来源
JOURNAL OF NEUROSURGERY-SPINE | 2004年 / 1卷 / 03期
关键词
lumbar spine; decompression; fusion; spondylolisthesis; stenosis; prospective clinical trial;
D O I
10.3171/spi.2004.1.3.0267
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Object. There is considerable debate among spine surgeons regarding whether fusion Should be used to augment decompressive surgery in patients with symptomatic lumbar spinal stenosis involving Grade I degenerative spondylolisthesis. The authors prospectively evaluated the outcomes of patients treated between 2000 and 2002 at two institutions to determine whether fusion improves functional outcome I year after surgery. Methods. Patients ranged in age from 50 to 81 years. They presented with degenerative Grade I (3- to 14-mm) spondylolisthesis and lumbar stenosis without gross instability (< 3 nun of motion a( the level of subluxation). Those ill whom previous surgery had been performed at the level of subluxation were excluded. Each patient completed Oswestry Disability Index (ODI) and Short Form-36 (SF-36) questionnaires preoperatively and at 6 to 12 month postoperatively. Some patients Underwent decompression alone (20 cases), whereas others underwent decompression and posterolateral instrumentation-assisted fusion (14 cases), at the treating surgeon's discretion. Baseline demographic data. radiographic features, and ODI and SF-36 scores were similar in both groups. The 1-year fusion rate was 93%. Both forms of surgery independently improved outcome compared with baseline status, based on ODI and SF-36 physical component summary (PCS) results (p < 0.001). Decompression combined with fusion led to an improvement in ODI scores of 27.5 points, whereas decompression alone was associated with a 13.6-point increase (p = 0.02). Analysis of the SF-36 PCS data also demonstrated a significant intergroup difference (p = 0.003) Conclusions. Surgery substantially improved 1-year outcomes based on established outcomes instruments in patients with Grade I spondylolisthesis and stenosis. Fusion was associated with greater functional improvement.
引用
收藏
页码:267 / 272
页数:6
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